Sunday, November 6, 2016

Oxygen levels can reset the circadian clocks

Circadian clock- this term is recollected only when one is jetlagged.
But scientists are curious to study the driving mechanism of biological rhythm. Light, food, and temperature are the known indications to influence circadian rhythms. But recently oxygen has also joined the list.
A new study published in Cell Metabolism has reported that circadian clocks of mice can be modulated by variations in surrounding oxygen levels. Researchers have shown that changing the oxygen levels by just 3%, twice a day, will synchronize mouse cells to a circadian rhythm. They have also surmised a protein HIF1α as a link between oxygen and circadian clock. Cells with low HIF1α levels won’t synchronize in response to oxygen variations.


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