Cancer cells’ camouflage exposed!
Due to the invisibility to the body’s immune system, cancer cells metastasize and spread throughout the body.
Researchers at The University of British Columbia have discovered a new mechanism explaining how tumours can outplay the immune system. Cancer cells genetically change and evolve over time. As they evolve, they may lose the protein called as interleukin-33 (IL-33). On the disappearance of IL-33, body’s immune system has no way of recognizing the cancer cells and they can begin to spread.
Loss of IL-33 occurs in epithelial carcinomas, meaning cancers that begin in tissues that line the surfaces of organs. These cancers include prostate, kidney breast, lung, uterine, cervical, pancreatic, skin and many others.
Further research will examine whether this finding could provide an effective cancer treatment in humans.
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