Thursday, October 27, 2016

Zika virus vaccines

Zika vaccines protected mice pups against neurological damage!
Zika is a virus spread mostly by the bite of an infected Aedes species mosquito. The virus can pass from an infected pregnant women to their fetus which can cause severe neurological birth defects.
Researchers at University of Pittsburgh have developed two vaccines against zika virus which have successfully carried immunity from female mice to pups.
Two vaccines- adenovirus zika vaccine and microneedle array zika vaccine showed immunity against zika after two weeks and six weeks of immunization respectively.
One week old pups were exposed to zika. All the pups from the mothers immunized with zika vaccines survived infection. Only a small percentage of the pups (~12.5%) from the unimmunized mothers survived.
Efforts are in progress to develop this vaccine for possible human clinical trials in the future.

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